Apple software, retail chiefs out in sweeping overhaul

SAN FRANCISCO (Reuters) - Apple Inc Chief Executive Tim Cook on Monday replaced the heads of its software and retail units in the company's most sweeping executive shake-up in a decade following embarrassing problems with its new mapping program and unpopular store-related decisions.


Software chief Scott Forstall, who oversaw the launch of the flawed mapping software and much criticized Siri voice-enabled assistant, will leave Apple next year and serve as an advisor to Cook in the meantime.


Forstall, seen as a polarizing figure inside Apple, had been billed as one of the future candidates to take the top job at Apple. He was the executive behind the panned Apple Maps app that the company announced with much fanfare in summer.


The moves, which come a little more than a year into Cook's tenure as CEO, were described by Apple as a way to increase "collaboration" across its hardware, software and services business.


"These changes show that Tim Cook is stamping his authority on the business," Ben Wood, analyst with CCS Insight, said. "Perhaps disappointed with the Maps issues, Forstall became the scapegoat."


Critics of the maps debacle, which led Cook to apologize to customers, had been calling for Forstall's head. "Does Apple have a Scott Forstall problem?" Fortune editor Philip Elmer Dewitt wrote on Sept 29.


The moves hand over substantially more responsibility to Cue, the head of Internet Software and Services who helped create the iTunes music store and App Store. The 23-year Apple veteran already is in charge of Cloud services and will take on Apple Maps and Siri.


Apple said a search is underway for a new retail chief to replace John Browett and that the retail team would report directly to Cook. Browett had riled up the retail store staff when he decided to reduce the number of retail employees.


Browett took over as head of Apple's retail stores earlier this year, replacing Ron Johnson, who went on to become the CEO of JC Penney.


Last week Apple delivered a second straight quarter of disappointing financial results, and iPad sales fell short of Wall Street's targets, marring its record of consistently blowing past investors' expectations.


(Reporting by Alexei Oreskovic; Editing by Richard Chang)


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Pole gets 30 years for killing 6 on Channel Island

























LONDON (AP) — A Polish builder who killed six people, including his wife and children, on the British Channel Island of Jersey has been sentenced to 30 years in prison.


Damian Rzeszowski, 31, carried out the knife attack in August 2011 at his home. He was said to have become depressed after his wife admitted to an affair.





















Rzeszowski was convicted of six counts of manslaughter but cleared of murder. On Monday, Judge Michael Birt sentenced him to 30 years in jail for each victim, but the sentences are to run concurrently.


Rzeszowski’s victims were his wife Izabela Rzeszowska, 30; 5-year-old daughter, Kinga; 2-year-old son, Kacper; father-in-law, Marek Gartska, 56; his wife’s friend Marta De La Haye, 34; and her 5-year-old daughter, Julia.


Europe News Headlines – Yahoo! News



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Anderson Cooper’s daytime show to end after two seasons

























NEW YORK (Reuters) – Anderson Cooper‘s venture into daytime is coming to an end after just two seasons after failing to find an audience in the crowded daytime talk show market.


Warner Bros Television, which syndicates “Anderson”, said on Monday the show will not be renewed after the current season ends in the summer of 2013.





















“The series will not be coming back for a third season in a marketplace that has become difficult to break through,” Warner Bros said in a statement.


The CNN anchor launched “Anderson,” subsequently retitled “Anderson Live,” in September 2011. But the show has struggled in the ratings despite retooling in the face of competition from veteran daytime hosts such as Ellen DeGeneres, and newcomers such as Katie Couric and “Survivor” host Jeff Probst.


“Anderson Live,” is attracting an average audience of about 1.4 million viewers, compared with around 4 million for “Dr. Phil” and about 2.3 million for “Katie,” according to TV ratings data.


Cooper issued a statement on Monday saying, “I am very proud of the work that our terrific staff has put into launching and sustaining our show for two seasons,” and added that he looked forward “to doing more great shows this season … I’m sorry that we won’t be continuing.”


TV stations carrying the show were first informed on Friday that the producers were not seeking renewal for another season.


Cooper, 45, and the winner of multiple Emmy award and a Peabody Award, continues as host of the CNN news program “Anderson Cooper 360” and has hosted the network’s New Year’s Eve special from Times Square for several years running.


Warner Bros is owned by Time Warner Inc.


(Reporting by Chris Michaud, editing by Jill Serjeant and Marguerita Choy)


TV News Headlines – Yahoo! News



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Residents' stories: Hurricane Sandy is windy, wet and loud


From Florida to New England, residents along the eastern seaboard are sharing their anecdotes, photos and videos of Hurricane Sandy. Below are excerpts from the latest dispatches from people living through the storm. All times on posts are ET. Interested in writing about your experiences? Share your story at Yahoo! Contributor Network and your Hurricane Sandy photos on Flickr.


4:10 p.m.


Power still on in Far Rockaway in Queens


QUEENS—Folks around town crowded the local grocery store, Food Dynasty, and purchased huge amounts of food. I was one of them. While some people left Far Rockaway, others in the houses near me and the apartment building I live in stayed. For a while, things seemed calmed. The wind picked up, then died down.


By late this morning, the wind hit the building pretty hard and I could hear the wind's blasts. While there has been rain, my apartment in Far Rockaway has not experienced flooding as of 2:10 p.m.


At times, though, the whole building seems to shake. Power has not been affected. One lone man left the building during the storm. I wasn't sure who he was or why he was leaving the building in the middle of the storm on his bicycle. I just sat in my room, waiting for the storm to blow over, thankful I still had power.


— Justin Samuels



4:03 p.m.


Wind gusts increasing in Morris County, New Jersey


DENVILLE, N.J.—Hurricane Sandy is a monster to be sure. My family and I have tied down everything we can outside. We have a make-shift camp in our basement for fear of downed tree limbs. We are as ready as we can be for power outages. We sit and wait for Sandy's approaching wrath.


Gusts have already started that will reach upward of 60 to 70 mph by this evening. The trees swaying in the back are a fearful reminder of the damage that this storm can bring to us in northern New Jersey. While we do not have the ocean to contend with, we do have many rivers and large trees that can damage our homes.


— Gioia Degenaars


3:59 p.m.


Sandy already bringing down tree limbs in New York


BROOKLYN—As the storm approaches New York City, residents are preparing to hunker down for the immediate future. As of 2 p.m. on Monday in Crown Heights (in central Brooklyn) the storm gusts are increasing and the streets are pretty much empty.


Trees are starting to go down and branches litter the street. The winds are not very high, but as they increase, the damage will be much greater. With expected gusts up to 75 mph and with trees already going down with gusts of around 35 mph, this has the potential to be damaging as the buildings start creating a wind-tunnel effect.


Transportation has ground to a halt and the schools are closed. As a transplant from the South, weathering a storm of this magnitude in the Northeast is a bit odd. As the flooding in areas in NYC increases, watching the news turns those of us not in the evacuation zones into outsiders looking in, as well.


— Melissa Walker


3:42 p.m.


A stormy wedding, thanks to Hurricane Sandy


QUEENS—My wedding is in four days. And while most of the preparations are ready, there are a few things that went wrong and need to be handled last-minute.


Last night, I was visiting my fiance's relatives in Massapequa. An hour after we got back to my mom's house in Elmont, we found out that they had to evacuate their home. His cousins in Long Beach were supposed to evacuate as well since they live right by the water, but they decided to stay home. They've since put up pictures on Facebook of the deluge outside their front steps as well as a snapshot of a reporter from ABC News coming over to interview them.


When I first heard about the magnitude of the storm, one of my first thoughts was, Oh no, I never got wedding insurance. And I sure as heck won't be able to get it now. When I was on the fence about purchasing wedding insurance, I thought that it ultimately wouldn't come in handy because the only disaster I could think of was a snowstorm, and those don't happen in this part of New York in November.


— Tricia Bangit


2:46 p.m.


On Upper East Side, Sandy is bad, but not horrible yet


MANHATTAN—Power remains on, the streets still have people and cars and, except for the pending arrival of the really bad weather, it seems like any other day.


Reports from friends and co-workers from the Jersey shore to Long Island say that the ocean is really kicking up and flooding has been anywhere from moderate to very bad. A friend reports that water was coming up to Ocean Avenue in Belmar, N.J., and another friend who decided to stay in her apartment in Battery Park is reporting water on the rise.


Do not be fooled, the worst is yet to come! Rain, wind and flooding will all increasingly worse as the day progresses. Stay inside or head to a shelter.


— TR Threston


1:27 p.m.


Blustering hollers of wind in New York


QUEENS—Earlier, I tweeted, "Hurricanes are always such teases. It's 2012. Bring on a real apocalypse already." Perhaps that was a bit arrogant, and I'll fully understand the irony should this hurricane murder me. However, I'm confident that it will sweep over with little impact on my life.


Outside, its effects are definitely being felt. The closure of the MTA for any given amount of time surely impacts business and industry substantially. I'm curious what operations may still be up and running during this windy mess. I've occasionally looked outside to see the trees moving back and forth from the gusts. The streets are mostly empty. I've seen no people today, but did see a single car driving around earlier.


I'm doing what I should do to stay safe: absolutely nothing. The real danger, if there is any, would be outside. So, I'm staying inside, and you should probably do the same. There are mandatory evacuations apparently happening in the major flood zones. I happen to be in a groove surrounded by Zone C, the least likely to flood. So, even if Zone A is in danger, my apartment building should be fine.


— Clayburn Griffin


11:01 a.m.


Hurricane Sandy takes aim at northeastern Pennsylvania


MILFORD, Pa. -- As of 10 a.m. on Monday morning, the track of Hurricane Sandy puts it just a few short hours away from here in northeastern Pennsylvania.


But already the winds are picking up in Pike County.


It is anticipated to make landfall along the Delaware coast, just south of Philadelphia. By the time the eye reaches inland, the winds are expected to cause it to be downgraded to a tropical storm. But by then, the damage for areas such as Pike County will have been done. Traditionally in this area, the rain will loosen the ground beneath trees and power poles. The high winds then rip these from the ground. In the past power has been off for days and weeks at a time. With the predictions calling for this storm to be worse than Irene of just two years ago, residents are gearing up for the worst: They're buying up water and staple foods at our local Wal-Mart, Kmart and other grocery stores. Even convenience stores like the Turkey Hill in Milford are feeling the panic.


— Charles B Reynolds


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Lilly trials boost amyloid-protein link to Alzheimer’s-analysis

























(Reuters) – Levels of a protein believed to be a main cause of Alzheimer’s disease rose in the blood of patients treated with Eli Lilly‘s experimental drug in late-stage trials, suggesting the protein, beta amyloid, was removed from the brain as intended, researchers said on Monday.


Lilly in August disclosed that its drug solanezumab did not significantly arrest progression of the memory-robbing disease in the pair of Phase III studies, which tested patients with mild to moderate symptoms of Alzheimer’s.





















But the company later said an analysis of combined data from the two trials suggested the drug significantly slowed cognitive decline in patients with only mild symptoms, although it did not slow the decline of their physical function.


The finding from the pooled trial data helped restore some faith in the closely followed Lilly drug – that it might hold promise in treating patients who have not yet developed symptoms or who are in the very earliest stages of the disease.


Researchers on Monday, attending the Clinical Trials in Alzheimer’s Disease (CTAD) annual scientific meeting in Monaco, said an independent analysis of the trial data suggested that beta amyloid was removed from the brain into the bloodstream of patients taking solanezumab.


“The results support continued interest in amyloid as a therapeutic target in Alzheimer’s disease research,” CTAD said in a release.


Rachelle Doody, an Alzheimer’s disease researcher from Baylor School of Medicine who led the analysis, said the removal of amyloid from the brain into the blood – and slight cognitive improvement seen – lend credence to amyloid as a culprit in the disease.


“The beta amyloid biomarker results in the trial support the small, yet significant cognitive benefit” seen with the anti-amyloid approach, Doody said.


Researchers said the studies support the earlier use of drugs like solanezumab, which target toxic amyloid plaques in the brain, to prevent symptoms of the disease. One such prevention study is slated to begin next year at Washington University in St. Louis, and includes use of the Lilly drug.


Researchers in Monaco said no changes were seen in any other biomarkers – meaning proteins or tissue changes believed associated with the disease – including another suspected leading culprit protein called tau.


Alzheimer’s is a progressive and ultimately fatal disease affecting an estimated 35 million people worldwide, CTAD said, adding the number is expected to exceed 115 million if nothing is done to slow or prevent the disease.


(Reporting By Ransdell Pierson; Editing by Steve Orlofsky)


Diseases/Conditions News Headlines – Yahoo! News



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SAP eyes "long" period of high sales growth: report

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Ukraine’s opposition doing well in election

























KIEV, Ukraine (AP) —


Ukraine’s opposition parties performed strongly in Sunday’s parliamentary vote, according to an exit poll, but President Viktor Yanukovych‘s party could still retain control of the legislature as its members are likely to sweep individual races across the country.





















The West is paying close attention to the conduct of the vote in the strategic ex-Soviet state, which lies between Russia and the European Union, and serves as a key conduit for transit of Russian energy supplies to many EU countries. An election deemed unfair would likely turn Ukraine further away from the West and toward Moscow.


Opposition parties alleged widespread violations on election day, such as vote-buying and a suspiciously high amount of home voting, but a local election monitor said those violations were isolated. Authorities insisted the election was honest and democratic.


The Fatherland party, led by the jailed charismatic former Prime Minister Yulia Tymoshenko, the Udar (Punch) of world boxing champion Vitali Klitschko and a nationalist party together received more than 50 percent of the vote on party lists, outnumbering Yanukovych’s Party of Regions and its traditional ally, the Communist Party.


Both Yanukovych’s and Tymoshenko’s parties claimed victory, saying the election showed the voters trust them to lead the country.


However, only half of the parliament’s 450 seats are split proportionately between the winning parties. The other half is filled by the winners of single-mandate races, where Yanukovych loyalists are expected to make a strong showing. In the election, each voter had two ballots, one with party names and one with the name of candidates in specific constituencies. No exit poll numbers were available for the individual races.


With Yanukovych under fire over the jailing of his top rival, Tymoshenko; rampant corruption and slow reforms, the opposition made a strong showing.


Tymoshenko’s Fatherland party is poised to get about 25 percent of the proportional vote, the Udar (Punch) led by world boxing champion Vitali Klitschko is set to get around 15 percent and the nationalist Svoboda (Freedom) party receives some 12 percent. The Party of Regions polled 28 percent and the Communists nearly 12 percent.


If the three opposition groups unite, they could get 127 parliament seats versus 98 seats gained by the Regions and Communists. The distribution of the remaining 225 seats is expected to be clear Monday.


Opposition forces hope to garner enough parliament seats to weaken Yanukovych’s power and undo the damage they say he has done: the jailing of Tymoshenko and her top allies, the concentration of power in the hands of the president, the snubbing of the Ukrainian language in favor of Russian, waning media freedoms, a deteriorating business climate and growing corruption.


The strong showing by the far-right Svoboda (Freedom) party which campaigns for the defense of the Ukrainian language and culture but is also infamous for xenophobic and anti-Semitic rhetoric emerged as a surprise and showed the widespread disappointment and anger with the ruling party.


It remains to be seen whether Tymoshenko’s group, Klitschko’s party and Svoboda can forge a strong alliance and challenge Yanukovych.


The election tainted by Tymoshenko’s jailing on charges of abuse of office has also been compromised by the creation of fake opposition parties, campaigns by politically unskilled celebrities, and the use of state resources and greater access to television by Yanukovych’s party.


___


Yuras Karmanau in Kiev contributed to this report.


Europe News Headlines – Yahoo! News



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Broadway takes few chances with superstorm coming

























NEW YORK (AP) — Broadway took the threat of the mammoth storm seriously, with theater owners canceling all Sunday evening and Monday performances of shows like “The Book of Mormon” ”Once” and “Mama Mia!” long before a drop of rain fell in Times Square.


“The safety and security of theatregoers and employees is everyone’s primary concern,” said Charlotte St. Martin, executive director of The Broadway League, which represents producers.





















Forecasts called for rain late Sunday or early Monday, and subway and public transportation service is to be halted Sunday evening, potentially stranding theatergoers. Refunds will be made available from the point of purchase.


Off-Broadway shows including “Stomp,” ”Bad Jews” and “Golden Child” were also canceled Sunday night. Most matinees on and off Broadway stayed open. Mondays are usually very light on Broadway, with most shows having that as their day off.


Some Broadway shows had no evening shows scheduled Sunday, including “Cyrano de Bergerac,” ”Annie,” ”Chaplin,” ”Enemy of the People,” ”Once,” ”Jersey Boys” and “Nice Work If You Can Get It.”


It was the most disruptive storm for the theater community since the threat of Hurricane Irene in late August 2011 prompted producers to cancel matinee and evening performances on Saturday and Sunday. While that hurricane mostly fizzled over New York, every show lost money because they were mostly limited to five or six performances that week.


Entertainment News Headlines – Yahoo! News



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Sandy: East Coast braces for epic hurricane, ‘life-threatening’ storm surge

Waves crash into a pier in Nags Head, N.C., Oct. 27, 2012. (Gerry Broome/AP)


[UPDATED: 6:00 p.m. ET]


"Superstorm." "The Perfect Storm." "Frankenstorm."


Whatever you want to call it, the East Coast is bracing for Hurricane Sandy, a "rare hybrid storm" that is expected to bring a life-threatening storm surge to the mid-Atlantic coast, Long Island Sound and New York harbor, forecasters say, with winds expected to be at or near hurricane force when it makes landfall sometime on Monday.


According to the National Hurricane Center, the Category 1 hurricane was centered about 270 miles southeast of Cape Hatteras, N.C., and 530 miles south of New York City early Sunday, carrying maximum sustained winds of 75 mph and moving northeast at 15 mph.


[Slideshow: Latest photos from Hurricane Sandy]


New York Mayor Michael Bloomberg ordered the immediate, mandatory evacuation for low-lying coastal areas, including Coney Island, the Rockaways, Brighton Beach, Red Hook and some parts of lower Manhattan along the East River.


"If you don't evacuate, you're not just putting your own life at risk," Mayor Bloomberg said at a news conference Sunday. "You're endangering first responders who may have to rescue you."


New Jersey Governor Chris Christie's message for residents was a bit more blunt. "Don't be stupid," Christie said Sunday afternoon, announcing the suspension of the state's transit system beginning at 12:01 a.m. Monday.


Earlier, New York Governor Andrew Cuomo announced the suspension of all MTA service--including subways, buses, Long Island Railroad and Metro North--beginning at 7 p.m. Sunday. New York City Public Schools will be closed on Monday, the mayor said. The New York Stock Exchange said its trading floor will be closed on Monday, too--the first such shutdown in 27 years, according to the Wall Street Journal.


[Related: Superstorm could impact 60 million]


Sandy is expected to continue on a parallel path along the mid-Atlantic coast later Sunday before making a sharp turn toward the northwest and southern New Jersey coastline on Monday--with the Jersey Shore and New York City in its projected path.


But the path is not necessarily the problem.


"Don't get fixated on a particular track," the Associated Press said. "Wherever it hits, the rare behemoth storm inexorably gathering in the eastern U.S. will afflict a third of the country with sheets of rain, high winds and heavy snow."


(FEMA)


A tropical storm warning has been issued between Cape Fear to Duck, N.C., while hurricane watches and high-wind warnings are in effect from the Carolinas to New England. The hurricane-force winds extend 175 miles from the epicenter of the storm, while tropical storm-force winds extend 500 miles--or roughly 1,000 miles end to end, making Sandy one of the biggest storms to ever hit the East Coast.


"We're looking at impact of greater than 50 to 60 million people," Louis Uccellini, head of environmental prediction for the National Oceanic and Atmospheric Administration, told the Associated Press.


"The size of this alone, affecting a heavily populated area, is going to be history making," Jeff Masters wrote on the Weather Underground blog.


President Barack Obama received a briefing on the storm at Federal Emergency Management Agency headquarters in Washington on Sunday. "My main message to everybody involved is that we have to take this seriously," President Obama said. "[We will] respond big and respond fast."


[Also read: Big storm scrambles presidential race schedules]


"I can be as cynical as anyone," Christie said on Saturday, announcing a state of emergency. "But when the storm comes, if it's as bad as they're predicting, you're going to wish you weren't as cynical as you otherwise might have been."


Meanwhile, emergency evacuations were being mulled by state officials in Connecticut, Massachusetts, Vermont, New Hampshire and even Maine.


In Virginia, Governor Bob McDonnell said 20,000 homes there had already reported power outages.


(Weather.com)


"This is not a coastal threat alone," said FEMA director Craig Fugate said during a media briefing early Sunday. "This is a very large area."


Forecasters also fear the combination of storm surge, high tide and heavy rain--between 3 and 12 inches in some areas--could be life-threatening for coastal residents.


According to the National Hurricane Center summary, coastal water levels could rise anywhere between 1 and 12 feet from North Carolina to Cape Cod, depending on the timing of the "peak surge." A surge of 6 to 11 feet is forecast for Long Island Sound and Raritan Bay, including New York Harbor.


The storm surge in New York Harbor during Hurricane Irene in September 2011, forecasters noted, was four feet.


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New test to improve HIV diagnosis in poor countries

























LONDON (Reuters) – Scientists have come up with a test for the virus that causes AIDS that is ten times more sensitive and a fraction of the cost of existing methods, offering the promise of better diagnosis and treatment in the developing world.


The test uses nanotechnology to give a result that can be seen with the naked eye by turning a sample red or blue, according to research from scientists at Imperial College in London published in the journal Nature Nanotechnology.





















“Our approach affords for improved sensitivity, does not require sophisticated instrumentation and it is ten times cheaper,” Molly Stevens, who led the research, told Reuters.


Simple and quick HIV tests that analyze saliva already exist but they can only pick up the virus when it reaches relatively high concentrations in the body.


“We would be able to detect infection even in those cases where previous methods, such as the saliva test, were rendering a ‘false negative’ because the viral load was too low to be detected,” she said.


The test could also be reconfigured to detect other diseases, such as sepsis, Leishmaniasis, Tuberculosis and malaria, Stevens said.


Testing is not only crucial in picking up the HIV virus early but also for monitoring the effectiveness of treatments.


“Unfortunately, the existing gold standard detection methods can be too expensive to be implemented in parts of the world where resources are scarce,” Stevens said.


According to 2010 data from the World Health Organisation, about 23 million people living with HIV are in Sub-Saharan Africa out of a worldwide total of 34 million.


The virus is also spreading faster and killing more people in this part of the world. Sub-Saharan Arica accounted for 1.9 million new cases out of a global total of 2.7 million in the same year, and 1.2 million out of the 1.8 million deaths.


The new sensor works by testing serum, a clear watery fluid derived from blood samples, in a disposable container for the presence of an HIV biomarker called p24.


If p24 is present, even in minute concentrations, it causes the tiny gold nanoparticles to clump together in an irregular pattern that turns the solution blue. A negative result separates them into ball shapes that generate a red color.


The researchers also used the test to pick up the biomarker for Prostate Cancer called Prostate Specific Antigen, which was the target of previous work that Stevens did with collaborators at University of Vigo in Spain.


That sensor used tiny gold stars laden with antibodies that latched onto the marker in a sample and produced a silver coating that could be detected with microscopes.


Stevens and her collaborator on the new test, Roberto de la Rica, said they plan to approach not-for-profit global health organizations to help them manufacture and distribute the new sensor in low income countries.


(Editing by Jason Webb)


Health News Headlines – Yahoo! News



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